Case Report: Non-Hemophilic Hemosiderotic Synovitis

Abstract

Pigmented Villonodular Synovitis (PVNS) is a locally aggressive neoplastic synovial disease characterized by joint effusions, expansion of the synovium, and bony erosions. It typically affects patients between 30 and 40 years old and presents with recurrent atraumatic knee hemarthrosis. Diagnosis involves clinical assessment, MRI imaging, arthrocentesis, and biopsy.

Hemosiderotic synovitis is a rare synovial proliferative disorder caused by recurrent hemorrhages in the joint, commonly affecting the knee. The most frequent cause is hereditary clotting factor deficiency diseases such as hemophilia. However, we report a rare case of non-hemophilic hemosiderotic synovitis of the knee, where the patient had no history of bleeding diathesis. Histopathological examination provided the definitive diagnosis. Early recognition and awareness of this subtype can lead to timely treatment, reducing joint destruction and improving patient outcomes.